The protein p53 hides inside a possible key to curing cancer. “It is an important tumor suppressor that has mutated and is inactive in 50% of all human cancers. Therefore the search for its reactivation has been an achievement that oncology has pursued for a long time ”.
Using Stampede has revealed important information about p53. Direct interactions between a region of this molecule and DNA have been seen.
"Computing is reaching the point where it can have an impact on the development of new cancer therapies," explains Rommie Amaro of the University of Texas.