Test to detect oral cancer in saliva

Mar 11, 2016 | Oncology

Researchers from the Faculty of Chemical Sciences of the Complutense University of Madrid (UCM) have designed the first biosensor that can identify oral cancer by analyzing the simultaneous presence of two biomarkers in saliva.

This biosensor detects the presence of a protein, interleukin 8 (IL-8), and that of the messenger RNA (mRNA) associated with its expression in saliva samples. According to the article published in “Previous studies had shown that the levels of IL-8 and its associated mRNA are altered in oral cancer. Evidence to which is added that of other studies showing how the simultaneous detection of these two biomarkers of different nature - one protein and the other genetic - makes it possible to establish a more precise clinical diagnosis ”.